Nothing else works like CORID^® (amprolium) against coccidiosis.

• CORID is the first and only coccidiostat labeled for use as both a preventive and treatment therapy.
  
  
• Only CORID is formulated for use as a true solution in drinking water or as a drench.
  
  
• CORID has a unique mode of action.
  
  

CORID prevents coccidiosis, and its losses.¹

• In a trial, each day for 5 days, 6-week-old Holstein calves were inoculated with either 500 or 50 thousand coccidia oocysts (Eimeria spp.).
  
  
• Preventive therapy with CORID began on first day of inoculation and continued for 21 days.
  
  
• After 7 months, groups given CORID had gained significantly more weight than respective infected controls.
  
  
• Gains in groups treated with CORID were statistically equivalent to non-infected controls.
  
  

Preventive therapy with CORID pays off every day.²

• In two trials, 8-week-old male calves were treated with CORID for either 21 or 35 days; each test included untreated controls.
  
  
• Calves were weighed at 8, 11, 13, 16 and 20 weeks of age.
  
  
• In Trials 1 and 2, where CORID was administered for 21 days, there was a statistically significant weight gain observed in treated calves at 20 weeks of age: 23.8 lbs (P<0.005) and 35.72 lbs (P=0.072), respectively.
  
  
• The largest difference in gains (on a percentage basis) was recorded at Week 11, when calves were still receiving CORID.
  
  
• The trials where CORID was administered, it was demonstrated that returns on investment were 10:1 and 16:1, respectively.
  
  

Treatment with CORID reduces oocyst discharge by 99.8%.³

• In another trial, approximately 200,000 Eimeria spp. sporulated oocysts were administered orally to young Holstein calves.
  
  
• Calves received CORID 9.6% Oral Solution at the treatment dosage on one of three schedules (Days 1 to 4; Days 8 to 11; Days 15 to 18 after inoculation).
  
  
• Untreated, infected control animals were included as well as non-infected controls to compare environmental exposures to coccidia.
  
  
• Data showed that all treatment periods were effective in reducing oocyst production.
  
  
• Treatment beginning at Day 15, coinciding approximately with the first clinical signs of disease, showed a dramatic 99.8% reduction of oocyst shedding.
  
  
• Infected controls averaged a cumulative total of 124,726 oocysts/gram of feces for a 7-day monitoring period (Days 18 to 25 after inoculation); non-infected controls totalled 1,013 and calves treated with CORID during Days 15 to 18 totalled 230.
  
  

 

Please see also more detailed information on CORID for Prevention and Treatment of Coccidiosis from a Merial Technical Bulletin.

 

References

1. Fitzgerald PR, Mansfield ME. Effects of bovine coccidiosis on certain blood components, feed consumption, and body weight changes of calves. Am J Vet Res 1972;33(7):1391-1397(Ref3).

2. Greiner EG, Saunders J. Cost Benefit Analysis of Feeding Amprolium Crumbles to Prevent Clinical Coccidiosis in Dairy Calves. Agri-Practice 1984;5(2):6-9.

3. Peardon DL, Bilkovich FR, Todd AC, Hoyt HH. Trials of candidate bovine coccidiostats: efficacy of amprolium, lincomycin, sulfamethazine, chloroquine sulfate, and diphenthane-70. Am J Vet Res 1965;26:683-687.